Drug Metabolism and pharmacokinetics Analysis Platform
DruMAP, a drug metabolism and pharmacokinetics (DMPK) analysis platform, consists of a database for DMPK parameters and programs that can predict many DMPK parameters from the chemical structure of a compound. The DruMAP database contains data of DMPK parameters from curated public data and newly acquired experimental data obtained under unified conditions. It also contains predicted data using our prediction programs. Users can simultaneously predict several DMPK parameters for novel compounds.
A user manual is available here (Japanese only).
The current version contains the following chemical records.
|Number of records|
|All registered compounds||30,971|
|Freebase compounds ignoring stereo structure||25,622|
DruMAP: a Novel Drug Metabolism and Pharmacokinetics Analysis Platform (in preparation).
This research was supported by the Drug Discovery Support Promotion Project from Japan Agency for Medical Research and Development, AMED.